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The Angio-Fibrotic Switch of VEGF and CTGF in Proliferative Diabetic Retinopathy

BACKGROUND: In proliferative diabetic retinopathy (PDR), vascular endothelial growth factor (VEGF) and connective tissue growth factor (CTGF) cause blindness by neovascularization and subsequent fibrosis, but their relative contribution to both processes is unknown. We hypothesize that the balance b...

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Detalles Bibliográficos
Autores principales: Kuiper, Esther J., Van Nieuwenhoven, Frans A., de Smet, Marc D., van Meurs, Jan C., Tanck, Michael W., Oliver, Noelynn, Klaassen, Ingeborg, Van Noorden, Cornelis J. F., Goldschmeding, Roel, Schlingemann, Reinier O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443281/
https://www.ncbi.nlm.nih.gov/pubmed/18628999
http://dx.doi.org/10.1371/journal.pone.0002675