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Murine Leukemia Virus Spreading in Mice Impaired in the Biogenesis of Secretory Lysosomes and Ca(2+)-Regulated Exocytosis
BACKGROUND: Retroviruses have been observed to bud intracellularly into multivesicular bodies (MVB), in addition to the plasma membrane. Release from MVB is thought to occur by Ca(2+)-regulated fusion with the plasma membrane. PRINCIPAL FINDINGS: To address the role of the MVB pathway in replication...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443282/ https://www.ncbi.nlm.nih.gov/pubmed/18629000 http://dx.doi.org/10.1371/journal.pone.0002713 |