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Activity-Dependent Shedding of the NMDA Receptor Glycine Binding Site by Matrix Metalloproteinase 3: A PUTATIVE Mechanism of Postsynaptic Plasticity

Functional and structural alterations of clustered postsynaptic ligand gated ion channels in neuronal cells are thought to contribute to synaptic plasticity and memory formation in the human brain. Here, we describe a novel molecular mechanism for structural alterations of NR1 subunits of the NMDA r...

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Detalles Bibliográficos
Autores principales: Pauly, Thorsten, Ratliff, Miriam, Pietrowski, Eweline, Neugebauer, Rainer, Schlicksupp, Andrea, Kirsch, Joachim, Kuhse, Jochen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443283/
https://www.ncbi.nlm.nih.gov/pubmed/18629001
http://dx.doi.org/10.1371/journal.pone.0002681