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Evolution of C2H2-zinc finger genes and subfamilies in mammals: Species-specific duplication and loss of clusters, genes and effector domains

BACKGROUND: C2H2 zinc finger genes (C2H2-ZNF) constitute the largest class of transcription factors in humans and one of the largest gene families in mammals. Often arranged in clusters in the genome, these genes are thought to have undergone a massive expansion in vertebrates, primarily by tandem d...

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Detalles Bibliográficos
Autores principales: Tadepally, Hamsa D, Burger, Gertraud, Aubry, Muriel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443715/
https://www.ncbi.nlm.nih.gov/pubmed/18559114
http://dx.doi.org/10.1186/1471-2148-8-176