A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine

BACKGROUND: p53 is an important tumour suppressor with a known role in the later stages of colorectal cancer, but its relevance to the early stages of neoplastic initiation remains somewhat unclear. Although p53-dependent regulation of Wnt signalling activity is known to occur, the importance of the...

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Detalles Bibliográficos
Autores principales: Reed, Karen R, Meniel, Valerie S, Marsh, Victoria, Cole, Alicia, Sansom, Owen J, Clarke, Alan R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443808/
https://www.ncbi.nlm.nih.gov/pubmed/18533991
http://dx.doi.org/10.1186/1471-2407-8-162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443808/
https://www.ncbi.nlm.nih.gov/pubmed/18533991
http://dx.doi.org/10.1186/1471-2407-8-162

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