Massively Parallel Interrogation of Aptamer Sequence, Structure and Function

BACKGROUND: Optimization of high affinity reagents is a significant bottleneck in medicine and the life sciences. The ability to synthetically create thousands of permutations of a lead high-affinity reagent and survey the properties of individual permutations in parallel could potentially relieve t...

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Detalles Bibliográficos
Autores principales: Fischer, Nicholas O., Tok, Jeffrey B.-H., Tarasow, Theodore M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444025/
https://www.ncbi.nlm.nih.gov/pubmed/18628955
http://dx.doi.org/10.1371/journal.pone.0002720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444025/
https://www.ncbi.nlm.nih.gov/pubmed/18628955
http://dx.doi.org/10.1371/journal.pone.0002720

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