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Massively Parallel Interrogation of Aptamer Sequence, Structure and Function
BACKGROUND: Optimization of high affinity reagents is a significant bottleneck in medicine and the life sciences. The ability to synthetically create thousands of permutations of a lead high-affinity reagent and survey the properties of individual permutations in parallel could potentially relieve t...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444025/ https://www.ncbi.nlm.nih.gov/pubmed/18628955 http://dx.doi.org/10.1371/journal.pone.0002720 |