Oncogenic BRAF Regulates Melanoma Proliferation through the Lineage Specific Factor MITF

The Microphthalmia-associated transcription factor (MITF) is an important regulator of cell-type specific functions in melanocytic cells. MITF is essential for the survival of pigmented cells, but whereas high levels of MITF drive melanocyte differentiation, lower levels are required to permit proli...

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Detalles Bibliográficos
Autores principales: Wellbrock, Claudia, Rana, Sareena, Paterson, Hugh, Pickersgill, Helen, Brummelkamp, Thijn, Marais, Richard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444043/
https://www.ncbi.nlm.nih.gov/pubmed/18628967
http://dx.doi.org/10.1371/journal.pone.0002734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444043/
https://www.ncbi.nlm.nih.gov/pubmed/18628967
http://dx.doi.org/10.1371/journal.pone.0002734

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