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The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue

BACKGROUND: Sulphur mustard gas, 2, 2'-dichlorodiethyl sulphide (HD), is a chemical warfare agent. Both mustard gas and its monofunctional analogue, 2-chloroethyl ethyl sulphide (CEES), are alkylating agents that react with and diminish cellular thiols and are highly toxic. Previously, we repor...

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Detalles Bibliográficos
Autores principales: Paromov, Victor, Qui, Min, Yang, Hongsong, Smith, Milton, Stone, William L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2446388/
https://www.ncbi.nlm.nih.gov/pubmed/18570648
http://dx.doi.org/10.1186/1471-2121-9-33