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Regulation of the V-ATPase along the Endocytic Pathway Occurs through Reversible Subunit Association and Membrane Localization

The lumen of endosomal organelles becomes increasingly acidic when going from the cell surface to lysosomes. Luminal pH thereby regulates important processes such as the release of internalized ligands from their receptor or the activation of lysosomal enzymes. The main player in endosomal acidifica...

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Detalles Bibliográficos
Autores principales: Lafourcade, Céline, Sobo, Komla, Kieffer-Jaquinod, Sylvie, Garin, Jérome, van der Goot, F. Gisou
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447177/
https://www.ncbi.nlm.nih.gov/pubmed/18648502
http://dx.doi.org/10.1371/journal.pone.0002758