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Disturbed Clockwork Resetting in Sharp-1 and Sharp-2 Single and Double Mutant Mice
BACKGROUND: The circadian system provides the basis to anticipate and cope with daily recurrent challenges to maintain the organisms' homeostasis. De-synchronization of circadian feedback oscillators in humans causes ‘jet lag’, likely contributes to sleep - , psychiatric - , metabolic disorders...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447179/ https://www.ncbi.nlm.nih.gov/pubmed/18648504 http://dx.doi.org/10.1371/journal.pone.0002762 |