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Functional Genomics Via Metabolic Footprinting: Monitoring Metabolite Secretion by Escherichia Coli Tryptophan Metabolism Mutants Using FT–IR and Direct Injection Electrospray Mass Spectrometry

We sought to test the hypothesis that mutant bacterial strains could be discriminated from each other on the basis of the metabolites they secrete into the medium (their ‘metabolic footprint’), using two methods of ‘global’ metabolite analysis (FT–IR and direct injection electrospray mass spectromet...

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Detalles Bibliográficos
Autores principales: Kaderbhai, Naheed N., Broadhurst, David I., Ellis, David I., Goodacre, Royston, Kell, Douglas B.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447367/
https://www.ncbi.nlm.nih.gov/pubmed/18629082
http://dx.doi.org/10.1002/cfg.302