Comparative Modelling Techniques: Where are we?

The enormous increase in data availability brought about by genomic projects is paralleled by an equally unprecedented increase in the expectations for new medical, pharmacological, environmental and biotechnological discoveries. Whether or not we will be able to meet (at least partially) these expe...

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Autor principal: Tramontano, Anna
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447371/
https://www.ncbi.nlm.nih.gov/pubmed/18629085
http://dx.doi.org/10.1002/cfg.306
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author Tramontano, Anna
author_facet Tramontano, Anna
author_sort Tramontano, Anna
collection PubMed
description The enormous increase in data availability brought about by genomic projects is paralleled by an equally unprecedented increase in the expectations for new medical, pharmacological, environmental and biotechnological discoveries. Whether or not we will be able to meet (at least partially) these expectations will depend on how well we will be able to interpret the data and translate the mono-dimensional information encrypted in genomes into a detailed understanding of its biological meaning at the phenotypic level. The process is far from being trivial, and the obstacles along the road are formidable: even the problem of identifying coding regions in eukaryotic genomes is not completely solved. Far more complex is identification of the function of the encoded proteins, and this will probably represent the most challenging problem for the next generations of scientists.
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spelling pubmed-24473712008-07-14 Comparative Modelling Techniques: Where are we? Tramontano, Anna Comp Funct Genomics Research Article The enormous increase in data availability brought about by genomic projects is paralleled by an equally unprecedented increase in the expectations for new medical, pharmacological, environmental and biotechnological discoveries. Whether or not we will be able to meet (at least partially) these expectations will depend on how well we will be able to interpret the data and translate the mono-dimensional information encrypted in genomes into a detailed understanding of its biological meaning at the phenotypic level. The process is far from being trivial, and the obstacles along the road are formidable: even the problem of identifying coding regions in eukaryotic genomes is not completely solved. Far more complex is identification of the function of the encoded proteins, and this will probably represent the most challenging problem for the next generations of scientists. Hindawi Publishing Corporation 2003-07 /pmc/articles/PMC2447371/ /pubmed/18629085 http://dx.doi.org/10.1002/cfg.306 Text en Copyright © 2003 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tramontano, Anna
Comparative Modelling Techniques: Where are we?
title Comparative Modelling Techniques: Where are we?
title_full Comparative Modelling Techniques: Where are we?
title_fullStr Comparative Modelling Techniques: Where are we?
title_full_unstemmed Comparative Modelling Techniques: Where are we?
title_short Comparative Modelling Techniques: Where are we?
title_sort comparative modelling techniques: where are we?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447371/
https://www.ncbi.nlm.nih.gov/pubmed/18629085
http://dx.doi.org/10.1002/cfg.306
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