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Melatonin therapy to improve nocturnal sleep in critically ill patients: encouraging results from a small randomised controlled trial

INTRODUCTION: Sleep disturbances are common in critically ill patients and when sleep does occur it traverses the day-night periods. The reduction in plasma melatonin levels and loss of circadian rhythm observed in critically ill patients receiving mechanical ventilation may contribute to this irreg...

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Detalles Bibliográficos
Autores principales: Bourne, Richard S, Mills, Gary H, Minelli, Cosetta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447606/
https://www.ncbi.nlm.nih.gov/pubmed/18423009
http://dx.doi.org/10.1186/cc6871