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Melatonin therapy to improve nocturnal sleep in critically ill patients: encouraging results from a small randomised controlled trial
INTRODUCTION: Sleep disturbances are common in critically ill patients and when sleep does occur it traverses the day-night periods. The reduction in plasma melatonin levels and loss of circadian rhythm observed in critically ill patients receiving mechanical ventilation may contribute to this irreg...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447606/ https://www.ncbi.nlm.nih.gov/pubmed/18423009 http://dx.doi.org/10.1186/cc6871 |