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OligoWalk: an online siRNA design tool utilizing hybridization thermodynamics

Given an mRNA sequence as input, the OligoWalk web server generates a list of small interfering RNA (siRNA) candidate sequences, ranked by the probability of being efficient siRNA (silencing efficacy greater than 70%). To accomplish this, the server predicts the free energy changes of the hybridizat...

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Detalles Bibliográficos
Autores principales: Lu, Zhi John, Mathews, David H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447759/
https://www.ncbi.nlm.nih.gov/pubmed/18490376
http://dx.doi.org/10.1093/nar/gkn250