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OligoWalk: an online siRNA design tool utilizing hybridization thermodynamics
Given an mRNA sequence as input, the OligoWalk web server generates a list of small interfering RNA (siRNA) candidate sequences, ranked by the probability of being efficient siRNA (silencing efficacy greater than 70%). To accomplish this, the server predicts the free energy changes of the hybridizat...
Autores principales: | Lu, Zhi John, Mathews, David H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447759/ https://www.ncbi.nlm.nih.gov/pubmed/18490376 http://dx.doi.org/10.1093/nar/gkn250 |
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