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Protein-protein interactions between lens vimentin and αB-crystallin using FRET acceptor photobleaching

PURPOSE: The R120G mutation of αB-crystallin is known to cause desmin-related myopathy, but the mechanisms underlying the formation of cataract are not clearly established. We hypothesize that alteration of protein–protein interaction between R120G αB-crystallin and lens intermediate filament protei...

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Detalles Bibliográficos
Autores principales: Song, Shuhua, Hanson, Mark J., Liu, Bing-Fen, Chylack, Leo T., Liang, Jack J-N.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447818/
https://www.ncbi.nlm.nih.gov/pubmed/18618007