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Ex vivo recovery and activation of dysfunctional, anergic, monocyte-derived dendritic cells from patients with operable breast cancer: critical role of IFN-alpha

BACKGROUND: Dendritic cells (DCs) play a crucial role in initiating effective cell-mediated immune responses, but are dysfunctional and anergic in breast cancer. Reversal of this dysfunction and establishment of optimal DC function is a key prerequisite for the induction of effective anti-cancer imm...

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Detalles Bibliográficos
Autores principales: Satthaporn, Sukchai, Aloysius, Mark M, Robins, Richard A, Verma, Chandan, Chuthapisith, Suebwong, Mckechnie, Alasdair J, El-Sheemy, Mohamad, Vassanasiri, Wichai, Valerio, David, Clark, David, Jibril, Jibril A, Eremin, Oleg
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447825/
https://www.ncbi.nlm.nih.gov/pubmed/18588665
http://dx.doi.org/10.1186/1471-2172-9-32