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Abundance of Early Functional HIV-Specific CD8(+) T Cells Does Not Predict AIDS-Free Survival Time

BACKGROUND: T-cell immunity is thought to play an important role in controlling HIV infection, and is a main target for HIV vaccine development. HIV-specific central memory CD8(+) and CD4(+) T cells producing IFNγ and IL-2 have been associated with control of viremia and are therefore hypothesized t...

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Detalles Bibliográficos
Autores principales: Schellens, Ingrid M. M., Borghans, José A. M., Jansen, Christine A., De Cuyper, Iris M., Geskus, Ronald B., van Baarle, Debbie, Miedema, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447878/
https://www.ncbi.nlm.nih.gov/pubmed/18648514
http://dx.doi.org/10.1371/journal.pone.0002745