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Prediction by Graph Theoretic Measures of Structural Effects in Proteins Arising from Non-Synonymous Single Nucleotide Polymorphisms

Recent analyses of human genome sequences have given rise to impressive advances in identifying non-synonymous single nucleotide polymorphisms (nsSNPs). By contrast, the annotation of nsSNPs and their links to diseases are progressing at a much slower pace. Many of the current approaches to analysin...

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Detalles Bibliográficos
Autores principales: Cheng, Tammy M. K., Lu, Yu-En, Vendruscolo, Michele, Lio', Pietro, Blundell, Tom L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447880/
https://www.ncbi.nlm.nih.gov/pubmed/18654622
http://dx.doi.org/10.1371/journal.pcbi.1000135