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Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease
Chlamydiae replicate in a vacuole within epithelial cells and commonly induce cell damage and a deleterious inflammatory response of unknown molecular pathogenesis. The chlamydial protease-like activity factor (CPAF) translocates from the vacuole to the cytosol, where it cleaves several cellular pro...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447887/ https://www.ncbi.nlm.nih.gov/pubmed/18625845 http://dx.doi.org/10.1083/jcb.200804023 |