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Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease

Chlamydiae replicate in a vacuole within epithelial cells and commonly induce cell damage and a deleterious inflammatory response of unknown molecular pathogenesis. The chlamydial protease-like activity factor (CPAF) translocates from the vacuole to the cytosol, where it cleaves several cellular pro...

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Detalles Bibliográficos
Autores principales:	Paschen, Stefan A., Christian, Jan G., Vier, Juliane, Schmidt, Franziska, Walch, Axel, Ojcius, David M., Häcker, Georg
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447887/ https://www.ncbi.nlm.nih.gov/pubmed/18625845 http://dx.doi.org/10.1083/jcb.200804023

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