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Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies
Lamin A mutations cause many diseases, including cardiomyopathies and Progeria Syndrome. The covalent attachment of small ubiquitin-like modifier (SUMO) polypeptides regulates the function of many proteins. Until now, no examples of human disease-causing mutations that occur within a sumoylation con...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447889/ https://www.ncbi.nlm.nih.gov/pubmed/18606848 http://dx.doi.org/10.1083/jcb.200712124 |