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Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation

Atherosclerotic plaques develop in regions of the vasculature associated with chronic inflammation due to disturbed flow patterns. Endothelial phenotype modulation by flow requires the integration of numerous mechanotransduction pathways, but how this is achieved is not well understood. We show here...

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Detalles Bibliográficos
Autores principales: Liu, Yunhao, Sweet, Daniel Timothy, Irani-Tehrani, Mohamad, Maeda, Nobuyo, Tzima, Ellie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447891/
https://www.ncbi.nlm.nih.gov/pubmed/18606845
http://dx.doi.org/10.1083/jcb.200709176