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Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation
Atherosclerotic plaques develop in regions of the vasculature associated with chronic inflammation due to disturbed flow patterns. Endothelial phenotype modulation by flow requires the integration of numerous mechanotransduction pathways, but how this is achieved is not well understood. We show here...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447891/ https://www.ncbi.nlm.nih.gov/pubmed/18606845 http://dx.doi.org/10.1083/jcb.200709176 |