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Estimating the efficiency of benzodiazepines on GABA(A) receptors comprising γ1 or γ2 subunits

BACKGROUND AND PURPOSE: Heterologous expression of α1, β2 and γ2S(γ1) subunits produces a mixed population of GABA(A) receptors containing α1β2 or α1β2γ2S(γ1) subunits. GABA sensitivity (lower in receptors containing γ1 or γ2S subunits) and the potentiation of GABA-activated chloride currents (I(GAB...

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Detalles Bibliográficos
Autores principales: Baburin, I, Khom, S, Timin, E, Hohaus, A, Sieghart, W, Hering, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2451336/
https://www.ncbi.nlm.nih.gov/pubmed/18604239
http://dx.doi.org/10.1038/bjp.2008.271