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Estimating the efficiency of benzodiazepines on GABA(A) receptors comprising γ1 or γ2 subunits
BACKGROUND AND PURPOSE: Heterologous expression of α1, β2 and γ2S(γ1) subunits produces a mixed population of GABA(A) receptors containing α1β2 or α1β2γ2S(γ1) subunits. GABA sensitivity (lower in receptors containing γ1 or γ2S subunits) and the potentiation of GABA-activated chloride currents (I(GAB...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2451336/ https://www.ncbi.nlm.nih.gov/pubmed/18604239 http://dx.doi.org/10.1038/bjp.2008.271 |