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Resting CD4(+ )effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function

BACKGROUND: Previously we described a system whereby human peripheral blood T cells stimulated for 8 days in a cytokine cocktail acquired effector function for contact-dependent induction of proinflammatory cytokines from monocytes. We termed these cells cytokine-activated (Tck) cells and found that...

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Detalles Bibliográficos
Autores principales: Brennan, Fionula M, Smith, Nicola MG, Owen, Sally, Li, Ching, Amjadi, Parisa, Green, Patricia, Andersson, Anna, Palfreeman, Andrew C, Hillyer, Philippa, Foey, Andrew, Beech, Jonathan T, Feldmann, Marc
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2452984/
https://www.ncbi.nlm.nih.gov/pubmed/18353171
http://dx.doi.org/10.1186/ar2390