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Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine
Alterations in the tumour suppressor p53 have been reported in tumour-associated stromal cells; however, the consequence of these alterations has not been elucidated. We investigated p53 status and responses to p53-activating drugs using tumour-associated stromal cells from A375 melanoma and PC3 pro...
Autores principales: | Dudley, A C, Shih, S-C, Cliffe, A R, Hida, K, Klagsbrun, M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453010/ https://www.ncbi.nlm.nih.gov/pubmed/18594537 http://dx.doi.org/10.1038/sj.bjc.6604465 |
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