Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis

Functional inactivation of the tumour suppressor protein p16(INK4a) constitutes a key event in the multistep process of pancreatic ductal cell transformation. However, the significance of p16 inactivation for complex and tissue-specific aspects of pancreatic cancer progression, such as angiogenesis...

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Detalles Bibliográficos
Autores principales: Schulz, P, Scholz, A, Rexin, A, Hauff, P, Schirner, M, Wiedenmann, B, Detjen, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453030/
https://www.ncbi.nlm.nih.gov/pubmed/18577984
http://dx.doi.org/10.1038/sj.bjc.6604457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453030/
https://www.ncbi.nlm.nih.gov/pubmed/18577984
http://dx.doi.org/10.1038/sj.bjc.6604457

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