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EGFR-targeting drugs in combination with cytotoxic agents: from bench to bedside, a contrasted reality

The clinical experience recently reported with epidermal growth factor receptor (EGFR)-targeting drugs confirms the synergistic interactions observed between these compounds and conventional cytotoxic agents, which were previously established at the preclinical stage. There are, however, examples of...

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Detalles Bibliográficos
Autores principales: Milano, G, Spano, J-P, Leyland-Jones, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453033/
https://www.ncbi.nlm.nih.gov/pubmed/18506149
http://dx.doi.org/10.1038/sj.bjc.6604373