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Elevated intracellular chloride level in albino visual cortex neurons is mediated by Na-K-Cl co-transporter

BACKGROUND: During development the switch from a depolarizing to a hyperpolarizing action of GABA is a consequence of a decrease of the Na(+)-K(+)-2Cl(- )co-transporter (NKCC1, Cl(-)-uptake) and increase of the K(+)-Cl(- )co-transporter (KCC2, Cl(-)-extrusion) expression. However albino visual corte...

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Detalles Bibliográficos
Autores principales: Diykov, Dmitry, Turchinovich, Andrey, Zoidl, Georg, Hoffmann, Klaus-Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453132/
https://www.ncbi.nlm.nih.gov/pubmed/18590550
http://dx.doi.org/10.1186/1471-2202-9-57