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Brevetoxin Forms Covalent DNA Adducts in Rat Lung Following Intratracheal Exposure

BACKGROUND: Human exposure to brevetoxins produced by the red tide organism, Karenia brevis, is an increasing public health concern. Using in vitro exposure of rat liver cells to brevetoxin B (PbTx-2), the primary toxin product of K. brevis, we previously showed that it formed C(27,28)-epoxy breveto...

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Detalles Bibliográficos
Autores principales: Radwan, Faisal F.Y., Ramsdell, John S.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453162/
https://www.ncbi.nlm.nih.gov/pubmed/18629316
http://dx.doi.org/10.1289/ehp.11068