iTRAQ Analysis of Complex Proteome Alterations in 3xTgAD Alzheimer's Mice: Understanding the Interface between Physiology and Disease

Alzheimer's disease (AD) is characterized by progressive cognitive impairment associated with accumulation of amyloid β-peptide, synaptic degeneration and the death of neurons in the hippocampus, and temporal, parietal and frontal lobes of the cerebral cortex. Analysis of postmortem brain tissu...

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Detalles Bibliográficos
Autores principales: Martin, Bronwen, Brenneman, Randall, Becker, Kevin G., Gucek, Marjan, Cole, Robert N., Maudsley, Stuart
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453232/
https://www.ncbi.nlm.nih.gov/pubmed/18648646
http://dx.doi.org/10.1371/journal.pone.0002750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453232/
https://www.ncbi.nlm.nih.gov/pubmed/18648646
http://dx.doi.org/10.1371/journal.pone.0002750

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