Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers

Cysteine-rich intestinal protein 1 (CRIP1) has been identified as a novel marker for early detection of cancers. Here we report on the use of phage display in combination with molecular modeling to identify a high-affinity ligand for CRIP1. Panning experiments using a circularized C7C phage library...

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Detalles Bibliográficos
Autores principales: Hao, Jihua, Serohijos, Adrian W. R., Newton, Gail, Tassone, Gina, Wang, Zuncai, Sgroi, Dennis C., Dokholyan, Nikolay V., Basilion, James P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453235/
https://www.ncbi.nlm.nih.gov/pubmed/18670594
http://dx.doi.org/10.1371/journal.pcbi.1000138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453235/
https://www.ncbi.nlm.nih.gov/pubmed/18670594
http://dx.doi.org/10.1371/journal.pcbi.1000138

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