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Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers
Cysteine-rich intestinal protein 1 (CRIP1) has been identified as a novel marker for early detection of cancers. Here we report on the use of phage display in combination with molecular modeling to identify a high-affinity ligand for CRIP1. Panning experiments using a circularized C7C phage library...
Autores principales: | Hao, Jihua, Serohijos, Adrian W. R., Newton, Gail, Tassone, Gina, Wang, Zuncai, Sgroi, Dennis C., Dokholyan, Nikolay V., Basilion, James P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453235/ https://www.ncbi.nlm.nih.gov/pubmed/18670594 http://dx.doi.org/10.1371/journal.pcbi.1000138 |
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