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Binding of α2ML1 to the Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) Reveals a New Role for LRP1 in the Human Epidermis

BACKGROUND: The multifunctional receptor LRP1 has been shown to bind and internalize a large number of protein ligands with biological importance such as the pan-protease inhibitor α2-macroglobulin (α2M). We recently identified Α2ML1, a new member of the α2M gene family, expressed in epidermis. α2ML...

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Detalles Bibliográficos
Autores principales: Galliano, Marie-Florence, Toulza, Eve, Jonca, Nathalie, Gonias, Steven L., Serre, Guy, Guerrin, Marina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453322/
https://www.ncbi.nlm.nih.gov/pubmed/18648652
http://dx.doi.org/10.1371/journal.pone.0002729