Liver Autoimmunity Triggered by Microbial Activation of Natural Killer T Cells

Humans with primary biliary cirrhosis (PBC), a disease characterized by the destruction of small bile ducts, exhibit signature autoantibodies against mitochondrial Pyruvate Dehydrogenase Complex E2 (PDC-E2) that crossreact onto the homologous enzyme of Novosphingobium aromaticivorans, an ubiquitous...

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Detalles Bibliográficos
Autores principales: Mattner, Jochen, Savage, Paul B., Leung, Patrick, Oertelt, Sabine S., Wang, Vivien, Trivedi, Omita, Scanlon, Seth T., Pendem, Krishna, Teyton, Luc, Hart, John, Ridgway, William M., Wicker, Linda S., Gershwin, M. Eric, Bendelac, Albert
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453520/
https://www.ncbi.nlm.nih.gov/pubmed/18474357
http://dx.doi.org/10.1016/j.chom.2008.03.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453520/
https://www.ncbi.nlm.nih.gov/pubmed/18474357
http://dx.doi.org/10.1016/j.chom.2008.03.009

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