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Hyperglycemia-Induced Reactive Oxygen Species Toxicity to Endothelial Cells Is Dependent on Paracrine Mediators

OBJECTIVE—This study determined the effects of high glucose exposure and cytokine treatment on generation of reactive oxygen species (ROS) and activation of inflammatory and apoptotic pathways in human retinal endothelial cells (HRECs). RESEARCH DESIGN AND METHODS—Glucose consumption of HRECs, human...

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Detalles Bibliográficos
Autores principales: Busik, Julia V., Mohr, Susanne, Grant, Maria B.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453610/
https://www.ncbi.nlm.nih.gov/pubmed/18420487
http://dx.doi.org/10.2337/db07-1520