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Activation of Estrogen Receptor Is Crucial for Resveratrol-Stimulating Muscular Glucose Uptake via Both Insulin-Dependent and -Independent Pathways

OBJECTIVE—Estradiol (E(2)) is known to modulate insulin sensitivity and, consequently, glucose homeostasis. Resveratrol (RSV), an agonist of estrogen receptor (ER), has exerted antihyperglycemic effects in streptozotocin-induced type 1 diabetic rats in our previous study and was also shown to improv...

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Detalles Bibliográficos
Autores principales: Deng, Jen-Ying, Hsieh, Po-Shiuan, Huang, Jiung-Pang, Lu, Long-Sheng, Hung, Li-Man
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453636/
https://www.ncbi.nlm.nih.gov/pubmed/18426865
http://dx.doi.org/10.2337/db07-1750