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Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores

INTRODUCTION: Osteoarthritis trials usually report average changes in visual analogue scale (VAS) pain, and examine the difference between treatment and placebo. We investigated whether dichotomous responder analysis provides a more informative interpretation of drug efficacy. METHODS: Merck supplie...

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Detalles Bibliográficos
Autores principales: Moore, R Andrew, Moore, Owen A, Derry, Sheena, McQuay, Henry J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453757/
https://www.ncbi.nlm.nih.gov/pubmed/18384679
http://dx.doi.org/10.1186/ar2394