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Extracellular heat shock protein 70 inhibits tumour necrosis factor-α induced proinflammatory mediator production in fibroblast-like synoviocytes

INTRODUCTION: It was recently suggested that heat shock protein (HSP)70, an intracellular protein, is a potential mediator of inflammatory disease when it is released into the extracellular compartment. Although elevated HSP70 levels have been identified in rheumatoid arthritis (RA) synovial tissues...

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Detalles Bibliográficos
Autores principales: Luo, Xinjing, Zuo, Xiaoxia, Zhou, Yaou, Zhang, Bing, Shi, Yongzhong, Liu, Meidong, Wang, Kangkai, McMillian, D Randy, Xiao, Xianzhong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453760/
https://www.ncbi.nlm.nih.gov/pubmed/18410682
http://dx.doi.org/10.1186/ar2399