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How much of protein sequence space has been explored by life on Earth?
We suggest that the vastness of protein sequence space is actually completely explorable during the populating of the Earth by life by considering upper and lower limits for the number of organisms, genome size, mutation rate and the number of functionally distinct classes of amino acids. We conclud...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2459213/ https://www.ncbi.nlm.nih.gov/pubmed/18426772 http://dx.doi.org/10.1098/rsif.2008.0085 |