Function and Structure of a Prokaryotic Formylglycine-generating Enzyme

Type I sulfatases require an unusual co- or post-translational modification for their activity in hydrolyzing sulfate esters. In eukaryotic sulfatases, an active site cysteine residue is oxidized to the aldehyde-containing C(α)-formylglycine residue by the formylglycine-generating enzyme (FGE). The...

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Detalles Bibliográficos
Autores principales: Carlson, Brian L., Ballister, Edward R., Skordalakes, Emmanuel, King, David S., Breidenbach, Mark A., Gilmore, Sarah A., Berger, James M., Bertozzi, Carolyn R.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2459300/
https://www.ncbi.nlm.nih.gov/pubmed/18390551
http://dx.doi.org/10.1074/jbc.M800217200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2459300/
https://www.ncbi.nlm.nih.gov/pubmed/18390551
http://dx.doi.org/10.1074/jbc.M800217200

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