Rapid discovery and optimization of therapeutic antibodies against emerging infectious diseases

Using a comprehensive set of discovery and optimization tools, antibodies were produced with the ability to neutralize SARS coronavirus (SARS-CoV) infection in Vero E6 cells and in animal models. These anti-SARS antibodies were discovered using a novel DNA display method, which can identify new anti...

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Detalles Bibliográficos
Autores principales: Rogers, J., Schoepp, R.J., Schröder, O., Clements, T.L., Holland, T.F., Li, J.Q., Li, J., Lewis, L.M., Dirmeier, R.P., Frey, G.J., Tan, X., Wong, K., Woodnutt, G., Keller, M., Reed, D.S., Kimmel, B.E., Tozer, E.C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2461042/
https://www.ncbi.nlm.nih.gov/pubmed/18480090
http://dx.doi.org/10.1093/protein/gzn027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2461042/
https://www.ncbi.nlm.nih.gov/pubmed/18480090
http://dx.doi.org/10.1093/protein/gzn027

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