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UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle

BACKGROUND: Human onchocerciasis or river blindness, caused by the filarial nematode Onchocerca volvulus, is currently controlled using the microfilaricidal drug, ivermectin. However, ivermectin does not kill adult O. volvulus, and in areas with less than 65% ivermectin coverage of the population, t...

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Detalles Bibliográficos
Autores principales: deC Bronsvoort, Barend M, Makepeace, Benjamin L, Renz, Alfons, Tanya, Vincent N, Fleckenstein, Lawrence, Ekale, David, Trees, Alexander J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464590/
https://www.ncbi.nlm.nih.gov/pubmed/18570639
http://dx.doi.org/10.1186/1756-3305-1-18