Tyrosine-kinase inhibition results in EGFR clustering at focal adhesions and consequent exocytosis in uPAR down-regulated cells of Head and Neck cancers

BACKGROUND: Antisense (AS) induced down-regulation of uPAR in ACCS adenoid-cyctic carcinoma cells decreased the cellular adhesion and invasion on various extracellular matrices. Additionally, ACCS-AS cells showed an increased EGFR expression and other behavioral similarities to NA-SCC, a typical hig...

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Detalles Bibliográficos
Autores principales: Abu-Ali, Samah, Fotovati, Abbas, Shirasuna, Kanemitsu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464604/
https://www.ncbi.nlm.nih.gov/pubmed/18519000
http://dx.doi.org/10.1186/1476-4598-7-47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464604/
https://www.ncbi.nlm.nih.gov/pubmed/18519000
http://dx.doi.org/10.1186/1476-4598-7-47

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