A simple and robust method for connecting small-molecule drugs using gene-expression signatures

BACKGROUND: Interaction of a drug or chemical with a biological system can result in a gene-expression profile or signature characteristic of the event. Using a suitably robust algorithm these signatures can potentially be used to connect molecules with similar pharmacological or toxicological prope...

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Detalles Bibliográficos
Autores principales: Zhang, Shu-Dong, Gant, Timothy W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464610/
https://www.ncbi.nlm.nih.gov/pubmed/18518950
http://dx.doi.org/10.1186/1471-2105-9-258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464610/
https://www.ncbi.nlm.nih.gov/pubmed/18518950
http://dx.doi.org/10.1186/1471-2105-9-258

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