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TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer’s disease and frontotemporal lobar degeneration

Autopsy studies have shown that about 55% of patients with frontotemporal lobar degeneration (FTLD) and 25% of patients with Alzheimer’s disease (AD) harbour TDP-43 immunoreactive pathological changes in their brains. Using ELISA, we investigated whether we could detect the presence, or increased am...

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Detalles Bibliográficos
Autores principales: Foulds, Penelope, McAuley, Erica, Gibbons, Linda, Davidson, Yvonne, Pickering-Brown, Stuart M., Neary, David, Snowden, Julie S., Allsop, David, Mann, David M. A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464623/
https://www.ncbi.nlm.nih.gov/pubmed/18506455
http://dx.doi.org/10.1007/s00401-008-0389-8