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Deleted in Liver Cancer 1 (DLC1) Negatively Regulates Rho/ROCK/MLC Pathway in Hepatocellular Carcinoma

AIMS: Deleted in liver cancer 1 (DLC1), a member of RhoGTPase activating protein (GAP) family, is known to have suppressive activities in tumorigenicity and cancer metastasis. However, the underlying molecular mechanisms of how DLC1 suppresses cell motility have not been fully elucidated. Rho-kinase...

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Detalles Bibliográficos
Autores principales: Wong, Carmen Chak-Lui, Wong, Chun-Ming, Ko, Frankie Chi-Fat, Chan, Lo-Kong, Ching, Yick-Pang, Yam, Judy Wai-Ping, Ng, Irene Oi-lin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464714/
https://www.ncbi.nlm.nih.gov/pubmed/18648664
http://dx.doi.org/10.1371/journal.pone.0002779